Stat3-y705
WebFeb 28, 2024 · As was expected, the STAT3(Y705) immunostaining was found predominantly in the neuronal nuclei of DRG indicating nuclear translocation of STAT3 activated in the Y705 position after sciatic nerve injury or intrathecal IL-6 injection. In addition, diffuse STAT3(Y705) immunofluorescence was present in the cytoplasm of … WebHuman Specificity Detects human STAT3 when phosphorylated at Y705. Source Monoclonal Rat IgG 2B Clone # 805435 Purification Protein A or G purified from hybridoma culture supernatant Immunogen Phosphopeptide containing the human STAT3 Y705 site Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose.
Stat3-y705
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WebWe found that NSC74859 inhibited p-STAT3(Y705) in SHH MB cells in a dose dependent manner and reduced the levels of EMT markers N-cadherin and slug compared to the … WebSep 1, 2024 · As a result, we demonstrated that import of STAT3 inside mitochondria requires Y705 phosphorylation by Jak, whereas its mitochondrial transcriptional activity, …
WebJul 8, 2024 · To genetically suppress phospho-Tyr705 of STAT3 (pY-STAT3), the Y705 phosphorylation STAT3 mutant (Y705A) in which Y705 was replaced with alanine was … WebWe found that NSC74859 inhibited p-STAT3(Y705) in SHH MB cells in a dose dependent manner and reduced the levels of EMT markers N-cadherin and slug compared to the DMSO control (Fig. 6 a, b & Additional file 1: Fig. S11a, b). We also analyzed STAT3 and STAT3 Y705 phosphorylation in IGFBP2 knockdown cells after stimulation with exogenous IGFBP2.
WebThe BD CBA Phospho Stat3 (Y705) Flex Set must be used in conjunction with a BD CBA Cell Signaling Master Buffer Kit (Cat. No. 560005, 100 tests, or 560006, 500 tests) and a flow … WebDot: STAT3 phospho Y705 peptide (aa700-710) ChIP: HepG2 (starved overnight) treated with IL-6. General notes This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply
WebSTAT3 Transcription Factor / metabolism* Serine / metabolism* Signal Transduction / drug effects Signal Transduction / radiation effects Spectrophotometry Statistics, Nonparametric Time Factors X-Rays Carbazoles Enzyme Inhibitors STAT3 Transcription Factor STAT3 protein, human Go 6976 Serine
WebHJC0152 inhibited p-STAT3 (Y705) levels in a time- and dose-dependent manner in the AGS and MKN45 cell lines, but had no significant effect on p-STAT3 (Y705) and total STAT3 expression levels (Figure 1C, D). In addition, HJC0152 significantly down-regulated c-Myc and cyclinD1, the downstream targets of STAT3. horno itimatWebDec 1, 2024 · In summary, we report on a mechanism involving BM-MSCs, the EMT–MET program and STAT3 signaling that reconciles early and late dissemination models. … We would like to show you a description here but the site won’t allow us. horn ok please full movie 2008 watch onlineWebPhospho-Stat3 (Tyr705) Antibody detects endogenous levels of Stat3 only when phosphorylated at Tyr705. The antibody does not cross-react with other Stat proteins … horno infinitonWebThis DuoSet IC ELISA contains the basic components required for the development of sandwich ELISAs to measure phosphorylated human and mouse STAT3 (Y705) in cell lysates. An immobilized capture antibody specific for STAT3 binds both phosphorylated and unphosphorylated STAT3. horno infernal terrariaWebJul 6, 2024 · STAT3在调控iNOS过程中发挥了重要的作用[17]，利用Western blot检测MA对LPS诱导的RAW264.7细胞STAT3的Y705和S727位点磷酸化产生影响，结果如图3(a)所示，LPS刺激能快速诱导胞内STAT3的酪氨酸和丝氨酸磷酸化，而经不同浓度(5，10，15，20 μmol/L)的MA处理细胞后，胞内p-STAT3(Y705 ... horn ok please fc roadhorno lainox manualWebPhospho-STAT3 (Tyr705) Antibody (12-9033-42) in Flow TOP: Intracellular staining of untreated (left) or 15-minute Human IL-6 Recombinant Protein ( Product # 14-8069-80 )-treated (right) normal human whole blood with Anti-Human CD3 APC ( Product # 17-0036-42) and Anti-Human/Mouse phospho-STAT3 (Y705) PE. horno io8042hgwd0