WebP glycoprotein (P gp) is a 170kD protein product of the ABCB1 gene located on chromosome 7q21. It consists of two membrane bound domains and two cytoplasmic nucleotide … WebHuman Permeability glycoprotein (P-gp) ELISA Kit Views (404) Publications (0) Catalog no (KTE60851) Datasheet Print Share Email Share 1 / Total 2 $ 359 Size and Unit Add to cart …
P-糖蛋白的核酸适配体筛选及应用研究
Web11. apr 2024 · Low brain penetration can be due to low blood-brain barrier (BBB) permeability, P-glycoprotein (Pgp) efflux, or high plasma protein binding. Successful methods include: parallel artificial membrane permeability assay (PAMPA)-BBB permeability, MDR1-MDCKII for Pgp efflux, B-P dialysis for fraction unbound, and in vivo … Web16. máj 2024 · Objective: To examine the role of permeability glycoprotein (P-gp) and its substrates in the mechanism of hyperprolactinemia. Data sources: PubMed and Google … horst a. fechner
Approaches to minimize the effects of P‐glycoprotein in drug …
WebThe higher efflux ratio was possibly caused by efflux transporters such as P-glycoprotein, a well-known receptor of CsA. The equilibrated intracellular concentration of CPs was estimated to be as low as 4.1-6.8 μM, which showed good consistency with the high efflux ratio. ... SCC-MS is promising as a reliable permeability assay for next ... Web渗透性糖蛋白 (Pgp)重组蛋白 Recombinant Permeability Glycoprotein (Pgp) CD243; ABCB1; ABC20; CLCS; GP170; MDR1; PGY1; P-Glycoprotein; Multidrug resistance protein 1; ATP … Web1. feb 2024 · P-glycoprotein (P-gp) is a drug efflux transporter that triggers doxorubicin (DOX) resistance. In this review, we highlight the molecular avenues regulating P-gp, such … horst 600