2024 Otoconin

Otoconin

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August undefined, 2024

WebSep 15, 2010 · The expression of otolin mRNA is restricted to the inner ear, and immunohistochemical analysis identified Otolin protein in support cells of the vestibular maculae and semi-circular canal cristae. Additionally, Otolin forms protein complexes with Cerebellin-1 and Otoconin-90, two protein constituents of the otoconia, when expressed … WebDec 22, 1998 · The major otoconin, estimated to constitute at least 90% of the total protein, appeared as a broad smear at a pI centered at 2.9 and with a molecular mass of ≈83 …

Sci-Hub Otoconin-90, the mammalian otoconial matrix protein, …

WebOtoconin-22 (Pote et al., 1993; Yaoi et al., 2003) was identified in amphibian otoconia, while its homolog Otoconin-90/95 was independently found in mammalian otoconia ( Wang et al., 1998;Verpy et ... WebMay 18, 2015 · Otoconin 90 specifically recruits other matrix components, which are essential for formation of the organic matrix of otoconia. Otoconin 90 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. educablocks offline

Mechanisms of Otoconia and Otolith Development

WebFor accuracy and to avoid contamination, have another person insert the drops if possible. Before using, hold the container in your hand for a few minutes in order to warm it. This … WebThe major otoconin of the aragonitic otoconia, otoconin-22 (OC22) of Xenopus laevis, has been sequenced (15). It contains 127 amino acid residues and is heavily glycosylated. Interest-ingly, OC22 is 37% identical to secretory phospholipase A2 (sPLA2); however, the protein has diverged in the calcium- WebWe investigated the roles of three proteins associated with the formation of otoconia including fetuin A, osteopontin (OPN), and otoconin 90 (OC90). In situ atomic force microscopy (AFM) studies of the effects of these proteins on the growth of atomic steps on calcite surfaces were performed to obtain insight into their effects on the growth kinetics. … construction contract review

Mammalian Otolin: A Multimeric Glycoprotein Specific to the

Nucleotide and amino acid sequences of bullfrog otoconin-22 …

WebMar 28, 2024 · Major protein of the otoconia, a calcium carbonate structure in the saccule and utricle of the ear. Together with OTOL1, acts as a scaffold for otoconia biomineralization: sequesters calcium and forms interconnecting fibrils between otoconia that are incorporated into the calcium crystal structure. Together with OTOL1, modulates calcite crystal ... WebJan 7, 2015 · We investigated the roles of three proteins associated with the formation of otoconia including fetuin A, osteopontin (OPN), and otoconin 90 (OC90). In situ atomic force microscopy (AFM) studies of the effects of these proteins on the growth of atomic steps on calcite surfaces were performed to obta … educabiz downloadWebSynonyms: OC90, Otoconin-90, Phospholipase A2 homolog, PLA2L, Otoconin 90 Gene ID 729330 You are here: Homepage Primary Antibodies OC90 Antibodies anti-OC90 antibody (AA 223-252) (Alkaline Phosphatase (AP)) (ABIN1919229) Service. Contact ... construction contract schedule

"WebMay 1, 2004 · Therefore, otoconin-22 mRNA in the mid-phase of stage 25 is transcribed into the protein, thereby forming the otoconia in the inner ear. Pote et al. (1993) identified … " - Otoconin

Otoconin

WebFind out which hearing solutions can help overcome different types of hearing loss. Find out how bone conduction works, and how it has helped thousands of people to enjoy the … WebThe ELISA kits listed below target Oc90, the symbol for the human gene, otoconin 90, and a member of the Phospholipase A2 family. The protein encoded by OC90 has a predicted amino acid length of 477, a mass of 51.7 kDa, and a secreted subcellular localization. There are currently 2 reported isoforms, as well as sites of glycosylation.

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WebMar 31, 2024 · The matrix protein in birds and mammals is called otoconin-90. In fish, a different protein is found with a smaller molecular weight -- otoconin 22 and otoconin … WebAug 1, 2003 · When Yaoi et al. cloned a cDNA encoding otoconin-22 from a cDNA library prepared from the endolymphatic sac of bullfrog, they were not surprised, of course, by the finding that bullfrog otoconin-22 was highly homologous to the already cloned Xenopus otoconin-22; what was surprising was to discover that ultimobranchialectomy …

WebMay 1, 2004 · Therefore, otoconin-22 mRNA in the mid-phase of stage 25 is transcribed into the protein, thereby forming the otoconia in the inner ear. Pote et al. (1993) identified otoconin-22, the major protein of aragonitic otoconia in the saccule of the inner ear of Xenopus. The otoconin-22 is considered to play a crucial role in depositing calcium … WebResults: 1) The average serum level of otoconin-90 in the BPPV group was significantly higher than that in the control group ( p < 0.05), whereas both the BMD T scores and serum 25-OH Vitamin D levels of the BPPV group were significantly lower than those of the control group ( p < 0.05). 2) There was a strong positive correlation between serum ...

WebAug 4, 2014 · Oc90 is the most abundant otoconin (Pote and Ross, 1991; Verpy et al., 1999; Wang et al., 1998) and is required for the otoconial matrix to form by speciﬁcally recruiting other components and calcium (Yang et al., 2011b; Zhao et al., 2007). While Oc90 has a similar role in seeding zebraﬁsh otoliths, it is not the major oto-conin (Sakagami ... Weboto· co· nia -ˈkō-nē-ə. : small crystals of calcium carbonate in the saccule and utricle of the ear that under the influence of acceleration in a straight line cause stimulation of the hair …

WebAug 1, 2003 · The bullfrog otoconin-22 encoded a protein consisting of 147 amino acids, including a signal peptide of 20 amino acids. The protein had cysteine residues identical in a number and position to those conserved among the secretory phospholipase A 2 family. The mRNA of bullfrog otoconin-22 was expressed in the ELS, including the PVLS and inner …

WebMar 29, 2024 · Wu Y, Han W, Yan W, Lu X, Zhou M, Li L, Guan Q, Fan Z. Increased Otolin-1 in Serum as a Potential Biomarker for Idiopathic Benign Paroxysmal Positional Vertigo Episodes. Front Neurol. 2024 May 13;11:367. doi: … educafactoryWebOct 4, 2016 · Oc90 is the most abundant otoconin (Pote and Ross, 1991; Verpy et al., 1999; Wang et al., 1998) and is required for the otoconial matrix to form by specifically recruiting other components and calcium (Yang et al., 2011b; Zhao et al., 2007). While Oc90 has a similar role in seeding zebrafish otoliths, it is not the major otoconin (Sakagami, 2000). educaholisticaWeb欢迎您访问武汉艾美捷科技有限公司官方网站！ construction contract schedule sampleWebOct 4, 2016 · Oc90 is the most abundant otoconin (Pote and Ross, 1991; Verpy et al., 1999; Wang et al., 1998) and is required for the otoconial matrix to form by specifically … educa fp jcylWebOtoconin is a structural glycoprotein found in the otoconial membrane of vertebrates. It is the major protein component of the otoconia .[6] For faster navigation, this Iframe is preloading the Wikiwand page for Otoconin . educads cursos gratisWebOtoconin 90 specifically recruits other matrix components, which are essential for formation of the organic matrix of otoconia. Otoconin 90 is encoded by a gene located on human chromosome 8, which consists of nearly 146 million base pairs, houses more than 800 genes and is associated with a variety of diseases and malignancies. educaformWebMar 31, 2024 · With the elucidation of the functional genome of the sponges (phylum Porifera), using the demosponge Suberites domuncula as a model system [], it became overt that the different metazoan taxa originate from one ancestor multicellular animal which is closely related to ancient sponge roots; this common ancestor evolved about 700 … educa city login